The world’s first tooth-regrowing drug has been approved for human trials

I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials.

The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. The intravenous drug deactivates the uterine sensitization-associated gene-1 (USAG-1) protein that suppresses tooth growth. Blocking USAG-1 from interacting with other proteins triggers bone growth and, voila, you got yourself some brand-new chompers. Pretty cool, right?

Human trials start in September, but the drug has been highly successful when treating ferrets and mice and did its job with no serious side effects. Of course, the usual caveat applies. Humans are not mice or ferrets, though researchers seem confident that it’ll work on homo sapiens. This is due to a 97 percent similarity in how the USAG-1 protein works when comparing humans to other species.

September’s clinical trial will include adults who are missing at least one molar but there’s a secondary trial coming aimed at children aged two to seven. The kids in the second trial will all be missing at least four teeth due to congenital tooth deficiency. Finally, a third trial will focus on older adults who are missing “one to five permanent teeth due to environmental factors.”

Takahashi and his fellow researchers are so optimistic about this drug that they predict the medicine will be available for everyday consumers by 2030. So in six years we can throw our toothbrushes away and eat candy bars all day and all night without a care in the world (don’t actually do that.)

While this is the first drug that can fully regrow missing teeth, the science behind it builds on top of years of related research. Takahashi, after all, has been working on this since 2005. Recent advancements in the field include regenerative tooth fillings to repair diseased teeth and stem cell technology to regrow the dental tissue of children.

This article originally appeared on Engadget at https://www.engadget.com/the-worlds-first-tooth-regrowing-drug-has-been-approved-for-human-trials-174423381.html?src=rss

Diet-friendly electric spoon enhances saltiness in food without actual salt

It’s almost too easy to take salt for granted these days given how common it is, but there was a time long ago when it was as valuable as gold. The role that salt and salty flavors play in our lives becomes all too apparent the moment we taste bland food, resulting in requesting for seasoning or, well, salt. Too much salt, however, put people’s health at risk, especially in cultures that lean towards very salty dishes. Replacing salt with healthier alternatives might just be a stopgap solution, so this innovative electric spoon simply tries to trick our tongues into tasting saltiness where there is barely any salt, allowing people to consume less salt without actual giving up their favorite flavor.

Designer: Kirin

Simple as it may look, our tongues are really complex systems of taste buds that may react different depending on their location and sensitivity to certain flavors. We’ve all been through science experiments related to the different areas of the tongue as well as how weak electrical currents, like those from a lemon, can affect our sense of taste. The latter is the principle behind this simple-looking electric salt spoon that aims to promote a healthier diet by reducing the amount of salt you need to use or consume just to get that salty flavor you love.

In a nutshell, the plastic and metal spoon passes a very weak electrical current on your tongue that tries to draw sodium ions that are normally dispersed and wasted, enhancing the salty flavor that would have otherwise been lost normally. This does mean that the salty flavor doesn’t just magically appear and there needs to still be some amount of salt in the dish for the magic to work. That said, the technology promises 1.5 times more saltiness, which mean you can use 1.5 times less salt to taste the same flavor. For a food culture like Japan that consumes 10g of salt daily, much higher than what the World Health Organization (WHO) recommends, that’s still a significant reduction.

The design of the spoon itself is pretty basic, and its large handle almost makes it look and feel like a child’s spoon. Operating the electric spoon is a simple matter of pressing a single button to turn it on and cycling through different electrical intensities. Amusingly, they recommend a proper way of holding the spoon and positioning your arm in order to maximize the effect of the weak current provided by a rechargeable lithium battery.

It might be a weird idea to be giving your tongue a tiny electrical shock to make food taste saltier, and the company behind the innovation promises it’s all within safe ranges. While it’s not going to make food magically taste better, the electric salt spoon offers a simpler, and somewhat more affordable way to enjoy low-salt diets without resorting to expensive salt alternatives.

The post Diet-friendly electric spoon enhances saltiness in food without actual salt first appeared on Yanko Design.

Another patient will get Neuralink’s brain implant

Neuralink will be able to surgically implant its device into another patient’s brain. The Wall Street Journal reports that the company was approved to move forward with a second procedure months after Noland Arbaugh became the first person to receive the brain implant.

Elon Musk said last week that the company was “accepting applications for the second participant” in the trial. The company began recruiting potential participants for its first clinical trial last year with the goal of bringing the technology to people with ALS, spinal cord injuries or other conditions that cause quadriplegia.

Neuralink has also reportedly come up with a potential fix for an issue that caused Arbaugh’s implant to malfunction about a month after his surgery. The company said earlier this month that some of the implant’s threads “retracted from the brain” causing the issue. Arbaugh recently told Bloomberg that software updates have since restored many of those capabilities. Neuralink has shared clips of Arbaugh, who is paralyzed from the neck down, playing chess, controlling a music player app and performing other activities. 

According to The Journal, Neuralink told the FDA that in a second procedure it would place the implant’s threads deeper into the patient’s brain to prevent them from moving as much as they did in Arbaugh’s case. The FDA is apparently on board with the changes. The company reportedly wants to complete the second surgery in June and has seen more than 1,000 people sign up for a chance to participate in the trial.

This article originally appeared on Engadget at https://www.engadget.com/another-patient-will-get-neuralinks-brain-implant-235059248.html?src=rss

EU investigating Meta over addiction and safety concerns for minors

Meta is back in hot water for its methods (or lack thereof) for protecting children. The European Commission has launched formal proceedings to determine whether the owner of Facebook and Instagram has violated the Digital Services Act (DSA) by contributing to children's social media addiction and not ensuring they have high levels of safety and privacy.

The Commission's investigation will specifically examine whether Meta is properly assessing and acting against risks brought on by its platforms' interfaces. It's concerned about how their designs could "exploit the weaknesses and inexperience of minors and cause addictive behavior, and/or reinforce so-called 'rabbit hole' effect. Such an assessment is required to counter potential risks for the exercise of the fundamental right to the physical and mental well-being of children as well as to the respect of their rights."

The proceedings will also explore whether Meta takes necessary steps to prevent minors from accessing inappropriate content, has effective age-verification tools and minors have straightforward, strong privacy tools, such as default settings.

The DSA sets standards for very large online platforms and search engines (those with 45 million or more monthly users in the EU) like Meta. Obligations for designated companies include transparency about advertising and content moderation decisions, sharing their data with the Commission and looking into risks their systems pose related to areas such as gender-based violence, mental health and protection of minors.

Meta responded to the formal proceedings by pointing to features such as parental supervision settings, quiet mode and it automatically restricting content for teens. "We want young people to have safe, age-appropriate experiences online and have spent a decade developing more than 50 tools and policies designed to protect them. This is a challenge the whole industry is facing, and we look forward to sharing details of our work with the European Commission," a Meta spokesperson told Engadget.

However, Meta has continuously failed to prioritize the safety of young people. Previous alarming incidents include Instagram's algorithm suggesting content that features child sexual exploitation and claims that it designs its platforms to be addictive to young people while suggesting psychologically harmful content, such as the promotion of eating disorders and body dysmorphia.

Meta has also famously served as a hub of misinformation for people of all ages. The Commission already launched formal proceedings against the company on April 30 due to concerns around deceptive advertising, data access for researchers and the lack of an "effective third-party real-time civic discourse and election-monitoring tool" before June's European Parliament elections, among other concerns. Earlier this year, Meta announced that CrowdTangle, which has publicly shown how fake news and conspiracy theories move around Facebook and Instagram, would be completely shut down in August.

This article originally appeared on Engadget at https://www.engadget.com/eu-investigating-meta-over-addiction-and-safety-concerns-for-minors-120709921.html?src=rss

EU investigating Meta over addiction and safety concerns for minors

Meta is back in hot water for its methods (or lack thereof) for protecting children. The European Commission has launched formal proceedings to determine whether the owner of Facebook and Instagram has violated the Digital Services Act (DSA) by contributing to children's social media addiction and not ensuring they have high levels of safety and privacy.

The Commission's investigation will specifically examine whether Meta is properly assessing and acting against risks brought on by its platforms' interfaces. It's concerned about how their designs could "exploit the weaknesses and inexperience of minors and cause addictive behavior, and/or reinforce so-called 'rabbit hole' effect. Such an assessment is required to counter potential risks for the exercise of the fundamental right to the physical and mental well-being of children as well as to the respect of their rights."

The proceedings will also explore whether Meta takes necessary steps to prevent minors from accessing inappropriate content, has effective age-verification tools and minors have straightforward, strong privacy tools, such as default settings.

The DSA sets standards for very large online platforms and search engines (those with 45 million or more monthly users in the EU) like Meta. Obligations for designated companies include transparency about advertising and content moderation decisions, sharing their data with the Commission and looking into risks their systems pose related to areas such as gender-based violence, mental health and protection of minors.

Meta responded to the formal proceedings by pointing to features such as parental supervision settings, quiet mode and it automatically restricting content for teens. "We want young people to have safe, age-appropriate experiences online and have spent a decade developing more than 50 tools and policies designed to protect them. This is a challenge the whole industry is facing, and we look forward to sharing details of our work with the European Commission," a Meta spokesperson told Engadget.

However, Meta has continuously failed to prioritize the safety of young people. Previous alarming incidents include Instagram's algorithm suggesting content that features child sexual exploitation and claims that it designs its platforms to be addictive to young people while suggesting psychologically harmful content, such as the promotion of eating disorders and body dysmorphia.

Meta has also famously served as a hub of misinformation for people of all ages. The Commission already launched formal proceedings against the company on April 30 due to concerns around deceptive advertising, data access for researchers and the lack of an "effective third-party real-time civic discourse and election-monitoring tool" before June's European Parliament elections, among other concerns. Earlier this year, Meta announced that CrowdTangle, which has publicly shown how fake news and conspiracy theories move around Facebook and Instagram, would be completely shut down in August.

This article originally appeared on Engadget at https://www.engadget.com/eu-investigating-meta-over-addiction-and-safety-concerns-for-minors-120709921.html?src=rss

An insulin pump software bug has injured over 200 people

The US Food and Drug Administration (FDA) has issued a Class I recall for the t:connect mobile app on iOS, which is used to monitor and control the t:slim X2 insulin pump used by people with diabetes. It was supposedly the first smartphone app that can program insulin doses that the FDA had approved. The agency issued the highest level of recall it could, because the app had serious software problems that could've have caused life-threatening conditions or even death. In fact, while there were no mortalities reported, the FDA received 224 injury reports as of April 15. 

According to the agency, version 2.7 of the t:connect mobile app had a bug that initiated a cycle wherein the app would crash and then would be relaunched by the iOS platform again and again. That apparently led to excessive Bluetooth communication that would drain the pump's battery and cause it to shut down earlier than the user would expect. Insulin pumps like the t:slim X2 are designed to automatically deliver insulin under the user's skin at set time intervals and whenever needed. They're supposed to take on the burden of managing the user's sugar levels so that they can go about their day without having to stop and inject themselves or if they're prone to getting hypo or hyperglycemia. 

If a pump shuts down without warning and before the user expects it to, it could lead to the under-delivery of insulin. As the FDA explained in its recall, that could result in hyperglycemia and even diabetic ketoacidosis, a life-threatening complication caused by the inability of the body to turn sugar into energy due to the lack of insulin. Tandem Diabetes Care, the company behind the app and the pump, sent all affected customers an emergency notice back in March. It advised them to update their app, to monitor their pump battery level closely and to carry backup insulin supplies. The FDA's recall notice could reach potentially affected customers who may not have seen the manufacturer's alerts, however, or who may have brushed it aside. Malfunctioning insulin pumps had been linked to multiple deaths in the past, so users may want to keep a close eye on theirs regardless of the brand. 

This article originally appeared on Engadget at https://www.engadget.com/an-insulin-pump-software-bug-has-injured-over-200-people-123056847.html?src=rss

Top 10 Medical Innovations That Are Changing & Upping The Healthcare Game

When it comes to taking care of our health, proactive action and a mindset of preparedness are always necessary. By taking the right precaution, and being prepared always, we can handle a medical emergency to the best of our ability. And the medical industry has been coming up with ingenious innovations, that are completely transforming the healthcare game. Designers have been coming up with new and improved, life-saving medical designs that not only boost medical care but also relieve some of the pressure from our tireless medical force. From an award-winning inflatable stretcher design to a copper jacket that can protect from diseases – these innovations are upping the medical arena.

1. Inflatable Stretcher

Dubbed the Inflatable Stretcher, and designed by Yu-Hsin Wu, a student of Taiwan’s Shih Chien University, this stretcher is a refreshing new upgraded version of the conventional stretcher. This stretcher carries patients from the site of the accident to the hospital in a safe and protected manner. The innovative stretcher cushions and protects the patient in the same way you would wrap someone or something in bubble wrap!

2. Cadence

Meet the Cadence concept design which is equipped with a pharmacy-grade pill sorting plate that makes it easier to organize pills, and place them where they belong. The tray is specially designed and features an opening for one day only, so you don’t accidentally place pills inside compartments that are already full. You could also simply pour the pills onto the tray, and then utilize the built-in spatula to move the exact number and kind towards the opening.

3. MedEasy

Called MedEasy, this thoughtful medicine box has been designed for the elderly. It functions as a dependable everyday companion for the older generation, as it helps them keep track of, manage, and stock their medicines. Loneliness is quite prevalent among senior citizens living alone, and this useful product aims to focus on their well-being and take better care of them, ensuring they don’t miss their medication or mix them up.

4. Withings Beamo

The Withings Beamo is a USB-shaped 4-in-1 multi-scope that keeps an eye on the vitals of your heart, and lungs, as well as temperature. Withings says that “Once, body temperature was the only health scan routinely taken at home. BeamO will revolutionize the measurement of the core vitals carried out during medical visits from the comfort of one’s own home. This crucial data will provide a vital overview of overall health or warning signs of potential areas of concern.”

5. The Ergostone Pebble

Called the Ergostone Pebble, this versatile and handy pouch is made using fine-grained sand from soapstone. The utilization of the natural mineral adds amazing heating and cooling properties to the pouch, which provides comfort to different parts of your body. The soapstone sand is tactile and placed inside the smooth shell of silicone, which allows the Pebble to gently conform to your body, while still offering heat or cold.

6. Full Metal Jacket

Meet the Full Metal Jacket by Vollebak! This jacket is built from germ-repelling metallic textiles. It utilizes a fabric with woven strands of copper, making it completely breathable, and flexible, and making sure it doesn’t make any sound as you move around. The jacket contains 11 kilometers of copper, and the apparel is strengthened by copper’s innate ability to kill any bacteria or virus that comes in contact with it.

7. Transcutaneous Oxygen Sensor

Designed by Deokhee Jeong, this wearable medical gadget helps patients suffering with any kind of disease related to peripheral capillaries like peripheral arterial disease (PAD). With such diseases, it is extremely important to take proactive action and be on your toes once it has been identified. This device keeps an eye on the earliest signs, by measuring the skin oxygen levels. The patch is wearable and is called the Transcutaneous Oxygen Sensor.

8. Wethm

Called Wethm this little device creates gentle vibrations of a train ride to slow your head down, and this is known as cardiovascular synchronization. This accessory is simple and yet effective as it uses soft and gentle sounds to lull our mind and body to sleep. This process provides us with a more peaceful and calmer state of sleep. Wethm utilizes soft buzzing to slowly wake you up, allowing you to feel fresh and recharged, ready to deal with the day!

9. Resilience Wheelchair

Dubbed the Resilience Wheelchair – this isn’t your ordinary wheelchair in the least. It transforms a conventional rugged motorized wheelchair into a rather elegant and classy chaise lounge. The wheelchair is available in choices of gray and chrome, which impart it with a sophisticated and refined touch. The chair is made from plastic and leather, providing you with utmost comfort, and a pretty pleasant tactile experience.

10. BHeart

Meet BHeart – the world’s first health tracker with an ‘endless battery’. Hearing the word endless with battery is really quite intriguing, and BHeart utilizes your own body movements to charge itself. This cuts down on your electricity bill and carbon emissions too. BHeart uses its patent-pending energy-harvesting technology to recharge itself using motion, body heat, and environmental light.

The post Top 10 Medical Innovations That Are Changing & Upping The Healthcare Game first appeared on Yanko Design.

GPT-4 performed close to the level of expert doctors in eye assessments

As learning language models (LLMs) continue to advance, so do questions about how they can benefit society in areas such as the medical field. A recent study from the University of Cambridge's School of Clinical Medicine found that OpenAI's GPT-4 performed nearly as well in an ophthalmology assessment as experts in the field, the Financial Times first reported.

In the study, published in PLOS Digital Health, researchers tested the LLM, its predecessor GPT-3.5, Google's PaLM 2 and Meta's LLaMA with 87 multiple choice questions. Five expert ophthalmologists, three trainee ophthalmologists and two unspecialized junior doctors received the same mock exam. The questions came from a textbook for trialing trainees on everything from light sensitivity to lesions. The contents aren't publicly available, so the researchers believe LLMs couldn't have been trained on them previously. ChatGPT, equipped with GPT-4 or GPT-3.5, was given three chances to answer definitively or its response was marked as null. 

GPT-4 scored higher than the trainees and junior doctors, getting 60 of the 87 questions right. While this was significantly higher than the junior doctors' average of 37 correct answers, it just beat out the three trainees' average of 59.7. While one expert ophthalmologist only answered 56 questions accurately, the five had an average score of 66.4 right answers, beating the machine. PaLM 2 scored a 49, and GPT-3.5 scored a 42. LLaMa scored the lowest at 28, falling below the junior doctors. Notably, these trials occurred in mid-2023. 

While these results have potential benefits, there are also quite a few risks and concerns. Researchers noted that the study offered a limited number of questions, especially in certain categories, meaning the actual results might be varied. LLMs also have a tendency to "hallucinate" or make things up. That's one thing if its an irrelevant fact but claiming there's a cataract or cancer is another story. As is the case in many instances of LLM use, the systems also lack nuance, creating further opportunities for inaccuracy.

This article originally appeared on Engadget at https://www.engadget.com/gpt-4-performed-close-to-the-level-of-expert-doctors-in-eye-assessments-131517436.html?src=rss

Breath Smarter, Not Harder: Introducing the World’s first Ai-Driven Smart Mask

The COVID-19 pandemic may be over, but the challenge of maintaining clean air persists. If there’s anything we’ve learned over the past year, it’s that conventional solutions are no longer sufficient when it comes to breathing fresh air. Common disposable and cloth masks do block some harmful elements, but they also block proper airflow. Some fan-enabled masks improve that situation slightly, but they still put an obstacle to some of the ordinary tasks that we do each day, especially when our voices are involved. Enter the age of AI-enabled technology. The innovative AI Air Mask not only filters out harmful elements with superior efficiency but also enhances airflow, ensuring that breathability and communication remain clear and unhindered. This is the next step in wearable health tech, promising not just cleaner air but also proactive health monitoring, all in a sleek, comfortable, and inclusive design.

Designer: Leandro Rolon

Click Here to Buy Now: $99 $299 ($200 off). Hurry, exclusive deal for YD readers only! Raised over $1.5 million.

We now live in a world where even the air inside our homes can be suspect, so one can only imagine how much worse the situation is outdoors. Just in time for the health scare that gripped the world, ATMOBLUE launched its first smart wearable purifier to address the need for clean, breathable air anywhere you go. It went beyond the minimum requirement of simply blocking harmful microorganisms to deliver a solution that was effective, customizable, and most importantly, comfortable.

Smart Adaptive Filtration: Employs intelligent sensors for adaptive, real-time purification, setting a new bar for air quality protection.

The first ATMOBLUE smart mask was practically a mini air purifier you could wear on your mouth. It utilized replaceable H13 HEPA filters to do the heavy lifting of blocking as much as 99.97% of harmful particles such as bacteria and PM2.5. But while some masks stopped there, ATMOBLUE went above and beyond to include a dual fan airflow system that removed that suffocating feeling whenever you wear a face mask. The result wasn’t just clean air but breathable air as well, increasing the comfort and confidence of wearers who made the investment in backing the project.

Premium Silicone Design: Engineered with superior silicone for unparalleled comfort, designed for all-day wear and redefining the protective gear experience.

As successful as that smart mask was, it isn’t yet the pinnacle of healthy breathing. Stepping into the limelight again, the creators of the ATMOBLUE Mask are presenting an even more advanced solution that leverages the hard-earned lessons of the past and applies the benefits of artificial intelligence to provide a more holistic view of the wearer’s health. This AI-driven Air Mask, an evolution of the original ATMOBLUE Mask, features a refined semi-transparent silicone body for premium comfort. It is equipped with a dynamic adaptive filtration system that intelligently senses environmental changes and auto-adjusts in real time for optimal protection.

AI-Enabled Bluetooth Microphone: Features a built-in mic for clear conversations and seamless AI assistant interaction, improving communication without compromising wearability.

But wait, there’s more! Wearing a mask always has the effect of muffling one’s voice, which can be an even bigger problem when trying to communicate. Addressing this issue head-on, the AI Air Mask is ingeniously equipped with an integrated microphone and Bluetooth connectivity, allowing you to convey your voice clearly and confidently. Elevating the experience further, this mask incorporates advanced voice recognition and AI capabilities, creating a symbiotic relationship with your AI smart assistant that transcends traditional communication barriers. Beyond enhancing dialogue, the AI Air Mask serves as a guardian of your well-being, continuously analyzing key health metrics such as temperature, respiratory patterns, and cough frequency, not only to provide better insight into your health but also to warn you of potential infection.

With the AI Air Mask, the creators of ATMOBLUE aren’t just offering an upgraded wearable but also an investment in a healthier future. That’s exactly the kind of investment you’re making with this sweet pre-sale deal that lets you not only reserve a spot but also get a 50% discount when the world’s first AI-driven smart mask launches next year.

Click Here to Buy Now: $99 $299 ($200 off). Hurry, exclusive deal for YD readers only! Raised over $1.5 million.

The post Breath Smarter, Not Harder: Introducing the World’s first Ai-Driven Smart Mask first appeared on Yanko Design.

The best ergonomic keyboards for 2024

It’s tough to give a blanket recommendation for ergonomics, as the term most accurately translates to “what works best for your body” — and all bodies are different. But if you’ve landed here, chances are you’re looking for a keyboard that’s easier on your shoulders, neck and wrists. Traditional keyboards keep your arms close together and force you to splay your hands outward. After a while, that can feel straining. By shifting the orientation of the keys, ergonomic keyboards can keep your upper body in a more neutral position, preventing you from twisting or over-extending your hands and arms. We’ve broken down the various features that make some boards more body-friendly than others and tested a handful to come up with the best ergonomic keyboards to suit different needs and preferences.

What to look for in an ergonomic keyboard

Alice vs split

Most ergonomic keyboard layouts fall into two categories: Alice and split. The former is a single board with the two halves of the keys rotated about 30 degrees apart at the bottom. The separation forms an A-shaped space between the keys — which has nothing to do with why it’s called an Alice layout, it’s just a happy coincidence. This subtle tweak pushes your elbows away from your ribs while keeping a straight line from your forearm to your middle knuckle. Using one, I pretty instantly felt more open along the front side of my body. This layout more closely resembles a traditional keyboard, so it should be easier for most folks to get used to than a fully split option.

Speaking of, split boards break the keys into two separate parts you can position individually. You can put them shoulder distance apart, bring them closer together or angle them as much as feels comfortable. You can also put your mouse between the halves, which may feel like an easier trip for your cursor hand. Personally, I like being able to put my current snack between the two parts.

Tenkeyless

You can find ergonomic keyboards with and without number pads. Not having those number keys on the right side lets you keep your mouse closer in, minimizing overall reach. But if you work with numbers a lot, you’ll likely want that pad included. Some programmable boards allow for the use of layers, which temporarily repurpose keys and can provide you with a ten-key option through clever remapping of letter keys.

Tenting and negative tilt

Tenting raises the middle of the keyboard up, so your hands move closer to a “handshake” position. Alice keyboards usually angle up towards the middle and always to a fixed degree, since the two sides are connected. Split boards often let you adjust the degree of tenting, going from flat to subtle to extreme lift.

You may have encountered keyboards with an optional lift at the back of the board, raising the top keys higher than the space bar. Every set of hands is different, but for most people, pulling the backs of the hands towards the forearms increases strain. Negative tilt has the opposite effect by sloping in the other direction, lowering the top number keys while raising the edge with the spacebar. Many Alice and some split keyboards offer an optional negative tilt. I found it was more comfortable to enable that feature when I’m standing, and I preferred to have the keys flat when sat at my desk.

Staggered vs columnar

This decision seems to be one of the more hotly-contested among ergo enthusiasts. A standard keyboard has staggered keys, with each row slightly offset to the rows above and below it — so the A key is about halfway between the Q and W above it. This is a holdover from vintage mechanical typewriters, in which each press activated a hammer that smashed ink onto paper in the shape of a letter. To fit the hammers as close together as possible, while still allowing for finger pads, the keys were staggered.

Columnar or ortholinear keyboards stack the keys in orderly columns, often with rows that are not linear. Proponents claim this makes the keys easier to reach. Whether that’s true will be up to your fingers to decide, but I can say for certain that if you learned to type on a staggered keyboard, switching to a columnar layout is tough. It will take days, possibly weeks before you instinctively hit the C key. The N, M and B keys don’t fare much better.

Programmable keys

With a few exceptions, most ergonomic keyboards will work with PCs or Macs as a standard typing input, but the use of function and hot keys may require some remapping. It can be as easy as an onboard switch to toggle between Mac and PC layouts, or as involved as downloading software to change up the keys. Some boards even include (or let you buy) extra keycaps to change, say, the Mac’s Command and Option keys to PC’s Start and Alt buttons.

For some boards, remapping or programming keys is a crucial feature. Gaming peripherals have extra keys that you can set to execute a series of keystrokes with the push of a single button. Keyboards that work with layers, in which a single button can perform several functions, typically allow you to change what those are. Some ergonomic keyboards have non-standard layouts, like thumb clusters with multiple keys near the space bar that you operate with your thumb. You’ll also be able to program those.

Other considerations

Ergonomic keyboards come in mechanical, membrane, and scissor switch versions. Which works best for you is, again, up to your preference. I won’t get too deep into the particulars here, but the short of it is that membrane and scissor switches are less customizable than mechanical and typically cheaper. Typing on them tends to be quieter and softer. Mechanical switches are more customizable, offer a more responsive typing experience and are usually pricier.

You’ll also have the option of wired or wireless ergonomic boards. All other things being equal, wired models are less expensive. Competitive gamers who rely on split-second responses may prefer the zero-lag of wired keyboards. Wired models also never run out of battery life and have fewer connectivity issues. But wireless keyboards keep your desk less cluttered.

Some ergonomic keyboards come with permanent or removable wrist or palm rests, which can be cushioned or hard. This is another area where opinions diverge: proponents claim they help you maintain a neutral hand position, while detractors say they put pressure on the tendons in your wrist. Ideally, your palms should be resting, not your wrists, and you might find you like having that support or you may find the pressure uncomfortable. 

A closeup shot of an ergonomic keyboard that shows the two sides splitting apart.
Photo by Amy Skorheim / Engadget

How we tested

All our guides begin with extensive research to figure out what’s out there and what’s worth testing. We consider brands with good reputations that we’ve heard good things about from colleagues and other trusted publications. For this guide, I looked for keyboards with ergonomic features like tenting, split keys, palm support and so on. I also zeroed in on boards that didn’t require a deep amount of familiarity with the vast and exhaustive world of custom keyboards.

Once I settled on ten boards, I acquired them and used each one for anywhere from a few days to a few weeks. I tried out the remapping and macros software and considered the comfort, design, price and durability of each model before arriving at picks I think will work best for the most people out there.

This article originally appeared on Engadget at https://www.engadget.com/best-ergonomic-keyboard-130047982.html?src=rss