Tag Archives: health care industry

The world’s first tooth-regrowing drug has been approved for human trials

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I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials.

The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. The intravenous drug deactivates the uterine sensitization-associated gene-1 (USAG-1) protein that suppresses tooth growth. Blocking USAG-1 from interacting with other proteins triggers bone growth and, voila, you got yourself some brand-new chompers. Pretty cool, right?

Human trials start in September, but the drug has been highly successful when treating ferrets and mice and did its job with no serious side effects. Of course, the usual caveat applies. Humans are not mice or ferrets, though researchers seem confident that it’ll work on homo sapiens. This is due to a 97 percent similarity in how the USAG-1 protein works when comparing humans to other species.

September’s clinical trial will include adults who are missing at least one molar but there’s a secondary trial coming aimed at children aged two to seven. The kids in the second trial will all be missing at least four teeth due to congenital tooth deficiency. Finally, a third trial will focus on older adults who are missing “one to five permanent teeth due to environmental factors.”

Takahashi and his fellow researchers are so optimistic about this drug that they predict the medicine will be available for everyday consumers by 2030. So in six years we can throw our toothbrushes away and eat candy bars all day and all night without a care in the world (don’t actually do that.)

While this is the first drug that can fully regrow missing teeth, the science behind it builds on top of years of related research. Takahashi, after all, has been working on this since 2005. Recent advancements in the field include regenerative tooth fillings to repair diseased teeth and stem cell technology to regrow the dental tissue of children.

This article originally appeared on Engadget at https://www.engadget.com/the-worlds-first-tooth-regrowing-drug-has-been-approved-for-human-trials-174423381.html?src=rss

The world’s first tooth-regrowing drug has been approved for human trials

Posted on by

I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials.

The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. The intravenous drug deactivates the uterine sensitization-associated gene-1 (USAG-1) protein that suppresses tooth growth. Blocking USAG-1 from interacting with other proteins triggers bone growth and, voila, you got yourself some brand-new chompers. Pretty cool, right?

Human trials start in September, but the drug has been highly successful when treating ferrets and mice and did its job with no serious side effects. Of course, the usual caveat applies. Humans are not mice or ferrets, though researchers seem confident that it’ll work on homo sapiens. This is due to a 97 percent similarity in how the USAG-1 protein works when comparing humans to other species.

September’s clinical trial will include adults who are missing at least one molar but there’s a secondary trial coming aimed at children aged two to seven. The kids in the second trial will all be missing at least four teeth due to congenital tooth deficiency. Finally, a third trial will focus on older adults who are missing “one to five permanent teeth due to environmental factors.”

Takahashi and his fellow researchers are so optimistic about this drug that they predict the medicine will be available for everyday consumers by 2030. So in six years we can throw our toothbrushes away and eat candy bars all day and all night without a care in the world (don’t actually do that.)

While this is the first drug that can fully regrow missing teeth, the science behind it builds on top of years of related research. Takahashi, after all, has been working on this since 2005. Recent advancements in the field include regenerative tooth fillings to repair diseased teeth and stem cell technology to regrow the dental tissue of children.

This article originally appeared on Engadget at https://www.engadget.com/the-worlds-first-tooth-regrowing-drug-has-been-approved-for-human-trials-174423381.html?src=rss

Research indicates that carbon dioxide removal plans will not be enough to meet Paris treaty goals

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New research conducted by the University of East Anglia (UEA) suggests that current carbon removal plans will not be enough to comply with Paris treaty goals to limit global warming to 1.5C, as reported in a study published by Nature. Scientists came to this conclusion by measuring the “emissions gap” between various national climate protection plans and what is actually needed to reach that goal.

This first-of-its-kind study found a gap of up to 3.2 billion tons of carbon dioxide (CO2) between current global plans to remove carbon from the atmosphere and what’s needed by 2050 to avoid the worst impacts of global warming. These impacts include heatwaves, floods, droughts, melting ice and sea level rise.

Since 2010, the United Nations environmental organization UNEP has taken similar measurements of this emissions gap. UEA’s research, which focuses primarily on CO2 removal, indicates that climate policy requires a more ambitious scope if we are to, well, survive as a species.

This means a more nuanced and robust approach that still keeps current carbon removal practices in place, but with a renewed focus on cutting emissions, renewable energy and minimizing deforestation. There are also novel carbon removal options that many nations have been slow to discuss, let alone implement.

These include advanced air filters systems and enhanced rock weathering. The latter is a technique in which carbon is removed from the atmosphere and stored in rocks. These techniques account for the removal of just 0.002 billion tons of C02 per year, compared to 3 billion tons through conventional options. The research indicates that these novel options must become more prevalent in the coming years to help meet that 1.5C threshold.

“The calculation should certainly be refined,” said the study’s lead author, Dr. William Lamb, of the MCC Applied Sustainability Science working group. “This much is clear: without a rapid reduction in emissions towards zero, across all sectors, the 1.5C limit will not be met under any circumstances.”

Co-author Dr. Naomi Vaughan, of the Tyndall Centre for Climate Change Research at UEA, added that “countries need more awareness, ambition and action on scaling up carbon dioxide removal methods together with deep emissions reductions to achieve the aspirations of the Paris Agreement."

To that end, even if every country sticks to promises regarding carbon removal targets, the amount of carbon removed would likely increase by a maximum of 0.5 billion tons by 2030 and 1.9 billion tons by 2050. The latest Intergovernmental Panel on Climate Change (IPCC) reported that it would take a removal increase of 5.1 billion tons to avoid the worst effects of climate change. So, yeah, there’s that gap of 3.2 billion tons.

We aren’t doomed, at least not yet anyways. The IPCC suggests an alternative scenario in which the world’s governments work together to reduce global energy demand, hastened by “politically initiated behavior.” In this scenario, carbon removal would increase by 2.5 billion tons by 2050 and alternative methods would help tighten the emissions gap to just 400 million tons. So we basically have to shift our entire society from one of self interest to one of global cooperation. It never hurts to dream and, hey, maybe AI will swoop in and save us. 

This article originally appeared on Engadget at https://www.engadget.com/research-indicates-that-carbon-dioxide-removal-plans-will-not-be-enough-to-meet-paris-treaty-goals-161113129.html?src=rss

Razer will refund Zephyr mask buyers due to bogus N95 claims

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Razer has to pay over $1.1 million to the Federal Trade Commission to settle complaints that it advertised its infamous Zephyr masks as N95-grade when it didn't get them certified at all. The gaming peripheral maker released Zephyr, its high-tech face mask with built-in RGB lighting, during the height of the pandemic. Half a year later, in early 2022, it introduced a "Pro" version that added voice amplification. Razer said back then the Zephyr was as effective as an N95 mask, but it later reneged on its claim and removed all references to "N95-grade" filters from its website and other marketing materials after it came out that the company didn't obtain proper certification. 

According to the FTC, Razer never submitted the Zephyr masks for testing to the FDA or the National Institute for Occupational Safety and Health (NIOSH), which gives out the official certification for masks that filter out 95 percent of airborne particles. Razer certainly isn't in the list of companies that manufacture N95 masks approved by NIOSH on its website. In the FTC's complaint, it accused Razer of only stopping its false advertising after consumer outrage. 

The company has to hand over what it earned from selling Zephyr — that's $1,071,254.33 in revenue — to the FTC, which the agency will then use to refund affected consumers. To note, the Zephyr masks cost customers at least $100. It will pay $100,000 in fine over its unsubstantiated health claims, as well. In addition to ordering Razer refund customers, the FTC also prohibited the company from making any claims that it's selling products that reduce the likelihood of being infected with or transmitting the COVID-19 virus without proper FDA approval. Razer has also been prohibited from claiming health benefits for its products without scientific evidence to support them, as well as from "falsely claiming that any product meets government-established standards when it has not."

This article originally appeared on Engadget at https://www.engadget.com/razer-will-refund-zephyr-mask-buyers-due-to-bogus-n95-claims-083127094.html?src=rss

Razer will refund Zephyr mask buyers due to bogus N95 claims

Posted on by

Razer has to pay over $1.1 million to the Federal Trade Commission to settle complaints that it advertised its infamous Zephyr masks as N95-grade when it didn't get them certified at all. The gaming peripheral maker released Zephyr, its high-tech face mask with built-in RGB lighting, during the height of the pandemic. Half a year later, in early 2022, it introduced a "Pro" version that added voice amplification. Razer said back then the Zephyr was as effective as an N95 mask, but it later reneged on its claim and removed all references to "N95-grade" filters from its website and other marketing materials after it came out that the company didn't obtain proper certification. 

According to the FTC, Razer never submitted the Zephyr masks for testing to the FDA or the National Institute for Occupational Safety and Health (NIOSH), which gives out the official certification for masks that filter out 95 percent of airborne particles. Razer certainly isn't in the list of companies that manufacture N95 masks approved by NIOSH on its website. In the FTC's complaint, it accused Razer of only stopping its false advertising after consumer outrage. 

The company has to hand over what it earned from selling Zephyr — that's $1,071,254.33 in revenue — to the FTC, which the agency will then use to refund affected consumers. To note, the Zephyr masks cost customers at least $100. It will pay $100,000 in fine over its unsubstantiated health claims, as well. In addition to ordering Razer refund customers, the FTC also prohibited the company from making any claims that it's selling products that reduce the likelihood of being infected with or transmitting the COVID-19 virus without proper FDA approval. Razer has also been prohibited from claiming health benefits for its products without scientific evidence to support them, as well as from "falsely claiming that any product meets government-established standards when it has not."

This article originally appeared on Engadget at https://www.engadget.com/razer-will-refund-zephyr-mask-buyers-due-to-bogus-n95-claims-083127094.html?src=rss

PUBG will take a nostalgia-infused trip back to its first map in May

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PUBG: Battlegrounds is somehow old enough to evoke nostalgia. The pioneering battle royale game, which entered Steam Early Access in 2017, will borrow a page from Fortnite’s playbook and honor its first map. Erangel Classic will recreate the old-school battlefield from the game’s inception for a limited two-week run in May and June.

Developer and publisher Krafton says the Erangel Classic map will reproduce the original’s concepts, graphics, atmosphere and UI. However, it will blend those with “modern tweaks” to deliver “the enjoyable gameplay experiences that players have grown accustomed to.” In other words, much like remasters of other classic games, the goal is to feel as close to the original as possible without chucking out all of its subtle quality-of-life improvements from the game’s evolution.

Still from PUBG, featuring a player taking cover behind a crate with an assault rifle. Rural scene with an old house behind.
Krafton

If the revamped map idea sounds familiar, Fortnite brought back its original 2018 island map late last year, breaking its records for player counts. (It peaked at 44.7 million players, marking its biggest day ever.) It’s easy to see why Krafton would want a piece of that action.

Specific nods to the original map include foggy and rainy weather to add an air of unpredictability. In addition, you’ll find bench weapons on the starting island (get ready to scramble for your favorite), and all weapons will have reduced recoil to match the original. It will also have a Tommy Gun in the care package, a vintage map UI and a “charmingly tacky font and graphics.”

The tiered rollout will arrive on PCs and consoles at different times, extending the playtime for those who own the game on multiple platforms (perhaps helping Krafton sell a few extra in-game items). Erangel Classic will be available in PUBG: Battlegrounds on PC from May 14 to May 28 and on consoles from May 23 to June 6, replacing the modern Erangel map during those periods. Krafton says the May 14 patch notes will go into more detail about all the map’s changes, so keep an eye out.

This article originally appeared on Engadget at https://www.engadget.com/pubg-will-take-a-nostalgia-infused-trip-back-to-its-first-map-in-may-194736249.html?src=rss

England’s NHS will provide artificial pancreas to thousands of diabetes patients

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England’s National Health Service (NHS) said on Tuesday that “tens of thousands of children and adults” with type 1 diabetes will receive an “artificial pancreas” to help manage their insulin levels. The hybrid closed loop system — a sensor under the skin that sends wireless readings to an externally worn pump, which delivers insulin as needed — can help patients avoid the risks of type 1 diabetes without worrying about finger sticks or injections.

This isn’t the first device of its kind. Tandem makes similar insulin pumps in the US after it received FDA authorization in 2019. Gizmodo notes that another company called iLet got FDA approval for a similar device last year. Although the NHS hasn’t said which specific device(s) its program will use, what’s different here is the nation’s publicly funded health care system providing them for free rather than as an exclusive privilege for the well-to-do. (Sigh.)

The hybrid closed loop system starts with a sensor implanted beneath the skin, which continually monitors glucose levels at regular intervals. The sensor sends that data wirelessly to a pump, worn externally, which delivers the proper insulin dosage. The “hybrid” part of its name comes from the fact that some user input, including entering carb intake, is still required in the otherwise self-regulating system.

The government agency gave an ultra-precise figure of 269,095 people in England living with type 1 diabetes, highlighting how many folks could potentially benefit from the rollout. The NHS says local branches will begin identifying patients for the program starting on Tuesday.

“Diabetes is a tough and relentless condition, but these systems make a significant, life-changing difference — improving both the overall health and quality of life for people with diabetes,” Colette Marshall, chief executive of Diabetes UK, wrote in the NHS’s press release announcing the rollout. “This really is a landmark moment and we’ll be working with the NHS and others to ensure a fair rollout that reaches people as quickly as possible.”

This article originally appeared on Engadget at https://www.engadget.com/englands-nhs-will-provide-artificial-pancreas-to-thousands-of-diabetes-patients-203236067.html?src=rss

England’s NHS will provide artificial pancreas to thousands of diabetes patients

Posted on by

England’s National Health Service (NHS) said on Tuesday that “tens of thousands of children and adults” with type 1 diabetes will receive an “artificial pancreas” to help manage their insulin levels. The hybrid closed loop system — a sensor under the skin that sends wireless readings to an externally worn pump, which delivers insulin as needed — can help patients avoid the risks of type 1 diabetes without worrying about finger sticks or injections.

This isn’t the first device of its kind. Tandem makes similar insulin pumps in the US after it received FDA authorization in 2019. Gizmodo notes that another company called iLet got FDA approval for a similar device last year. Although the NHS hasn’t said which specific device(s) its program will use, what’s different here is the nation’s publicly funded health care system providing them for free rather than as an exclusive privilege for the well-to-do. (Sigh.)

The hybrid closed loop system starts with a sensor implanted beneath the skin, which continually monitors glucose levels at regular intervals. The sensor sends that data wirelessly to a pump, worn externally, which delivers the proper insulin dosage. The “hybrid” part of its name comes from the fact that some user input, including entering carb intake, is still required in the otherwise self-regulating system.

The government agency gave an ultra-precise figure of 269,095 people in England living with type 1 diabetes, highlighting how many folks could potentially benefit from the rollout. The NHS says local branches will begin identifying patients for the program starting on Tuesday.

“Diabetes is a tough and relentless condition, but these systems make a significant, life-changing difference — improving both the overall health and quality of life for people with diabetes,” Colette Marshall, chief executive of Diabetes UK, wrote in the NHS’s press release announcing the rollout. “This really is a landmark moment and we’ll be working with the NHS and others to ensure a fair rollout that reaches people as quickly as possible.”

This article originally appeared on Engadget at https://www.engadget.com/englands-nhs-will-provide-artificial-pancreas-to-thousands-of-diabetes-patients-203236067.html?src=rss

Fitbit’s health chatbot will arrive later this year

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Like most other corners of the tech world, Google sees AI powering the next innovations in health technology. The company’s annual The Check Up event expanded on its plans to add a personal health chatbot to the Fitbit app, expand Google Lens for better skin condition searches and use a version of its Gemini chatbot in the medical field.

One of the more intriguing of Google’s announcements on Tuesday was more detail about an experimental AI feature for Fitbit users, briefly teased last year. Fitbit Labs will let owners draw correlations and “connect the dots” from health data tracked using their wearable devices. A chatbot in the mobile app will let you ask questions in natural language and create personalized charts to learn about your health.

The company hasn’t yet gone into great depth about the Fitbit chatbot, but an example it published Tuesday shows a user asking about potential connections between activity and sleep. The Fitbit assistant answered that the user’s days with higher activity scores correlated with better sleep (while cautioning not to assume that’s the only reason).

The Fitbit generative AI tool will arrive later this year. Google says it will (at least initially) only be available to Fitbit Premium subscribers with Android devices enrolled in the Fitbit Labs program.

Google screenshot of an upcoming Fitbit feature that answers personal health questions. The user's text box asks about connections between their activity and sleep, and the bot says that when they spend 58+ minutes in activity zones, their sleep score rose by nine points.
Google / Fitbit

The company sees Google Lens as filling some healthcare gaps where text-based searches fall short. It says a feature (introduced last year) that uses Lens to identify “visually similar matches from the web” for skin conditions is now available in over 150 countries. It can work even when you don’t know where to begin when describing a dermatological disorder.

In a similar light, Google has added new images and diagrams to its web results from reputable online sources to help you understand conditions like neck pain. Up next: The company sees the visual results powering its searches for more health conditions, including migraines, kidney stones and pneumonia. The visual search engine updates are expected to roll out over the next few months.

The company also mentioned that Fitbit and Google Research are partnering with health and wellness experts and other medical professionals to create a new AI model for health and wellness. The long-term goal is for the Gemini-powered large language model (LLM) to power its future AI features across Google’s various health offerings.

This article originally appeared on Engadget at https://www.engadget.com/fitbits-health-chatbot-will-arrive-later-this-year-210609008.html?src=rss

Fitbit’s health chatbot will arrive later this year

Posted on by

Like most other corners of the tech world, Google sees AI powering the next innovations in health technology. The company’s annual The Check Up event expanded on its plans to add a personal health chatbot to the Fitbit app, expand Google Lens for better skin condition searches and use a version of its Gemini chatbot in the medical field.

One of the more intriguing of Google’s announcements on Tuesday was more detail about an experimental AI feature for Fitbit users, briefly teased last year. Fitbit Labs will let owners draw correlations and “connect the dots” from health data tracked using their wearable devices. A chatbot in the mobile app will let you ask questions in natural language and create personalized charts to learn about your health.

The company hasn’t yet gone into great depth about the Fitbit chatbot, but an example it published Tuesday shows a user asking about potential connections between activity and sleep. The Fitbit assistant answered that the user’s days with higher activity scores correlated with better sleep (while cautioning not to assume that’s the only reason).

The Fitbit generative AI tool will arrive later this year. Google says it will (at least initially) only be available to Fitbit Premium subscribers with Android devices enrolled in the Fitbit Labs program.

Google screenshot of an upcoming Fitbit feature that answers personal health questions. The user's text box asks about connections between their activity and sleep, and the bot says that when they spend 58+ minutes in activity zones, their sleep score rose by nine points.
Google / Fitbit

The company sees Google Lens as filling some healthcare gaps where text-based searches fall short. It says a feature (introduced last year) that uses Lens to identify “visually similar matches from the web” for skin conditions is now available in over 150 countries. It can work even when you don’t know where to begin when describing a dermatological disorder.

In a similar light, Google has added new images and diagrams to its web results from reputable online sources to help you understand conditions like neck pain. Up next: The company sees the visual results powering its searches for more health conditions, including migraines, kidney stones and pneumonia. The visual search engine updates are expected to roll out over the next few months.

The company also mentioned that Fitbit and Google Research are partnering with health and wellness experts and other medical professionals to create a new AI model for health and wellness. The long-term goal is for the Gemini-powered large language model (LLM) to power its future AI features across Google’s various health offerings.

This article originally appeared on Engadget at https://www.engadget.com/fitbits-health-chatbot-will-arrive-later-this-year-210609008.html?src=rss