UK authorizes first gene therapy for treating sickle cell disease

In a landmark decision, the UK’s Medicines and Healthcare products Agency (MHRA) approved the use of a gene-editing therapy called Casgevy for patients with sickle cell disease and beta thalassemia — both of which are hereditary disorders related to genetic mutations of the red blood cells. The treatment, manufactured by Vertex, is the first-ever approved therapy that utilizes CRISPR-based gene editing technology to treat eligible patients.

The UK approval of the novel therapy is informed by two previous global clinical trials that indicated the treatment's efficacy. 97 percent of patients using Casgevy were relieved of severe pain associated with the blood disorders for at least 12 months after treatment during the trials. The results suggest that the gene editing treatment could replace the current standard for care. Stem cell therapy and bone marrow transplants are currently the only pathways to cure sickle cell disease and beta thalassemia, however, they involve a lot of risks.

Both sickle cell disease and beta thalassemia are blood disorders characterized by defective red blood cells that can’t carry oxygen, and require patients to get monthly blood transfusions that can be costly and time-consuming. Casgevy works by specifically targeting the genes in the bone marrow stem cells that produce faulty blood cells. For the treatment to work, a patient’s stem cells need to be extracted from their bone marrow, edited in a lab and then re-infused into the patient.

Despite its promising outlook, CRISPR-based therapies may not be easily available to the general public. Gene editing is an expensive endeavor. The Innovative Genomics Institute (IGI) estimates that the average CRISPR-based therapy will cost between $500,000 and $2 million per patient. The IGI has built out an ‘Affordability Task Force’ to tackle the issue of expanding access to these novel therapies.

Aside from costliness, gene editing therapies offer huge promise to innovate treatment pathways for rare conditions including neurodegenerative diseases, cancer and muscular atrophy. More importantly, this landmark approval for Casgevy “opens the door for further applications of CRISPR therapies in the future,” Prof Dame Kay Davies, a scientist from the University of Oxford, said. And new iterations of gene editing technologies may even surpass CRISPR in the future.

Casgevy is still being reviewed by regulatory agencies for safety standards in other countries, including the United States and Saudi Arabia. A marketing application, the first step towards approval for the therapy, was recently validated by the European Medicines Agency.

This article originally appeared on Engadget at https://www.engadget.com/uk-authorizes-first-gene-therapy-for-treating-sickle-cell-disease-184130989.html?src=rss

Researchers developed a gene-editing technology that reduces ‘bad’ cholesterol

In a trial run by Verve Therapeutics, a Cambridge–based biotech company, researchers discovered that a single infusion of a gene-editing treatment called VERVE-101 was able to reduce cholesterol levels in patients. This treatment was tested in individuals with hereditary conditions that made them susceptible to developing clogged arteries and heart attacks. Scientists were able to use CRISPR editing techniques to tweak liver gene cells. The researchers “turned off” a cholesterol-raising gene called PCSK9, which is found in the liver, in order to lower LDL-C — sometimes called "bad" cholesterol — which causes plaque to build up in arteries in the first place.

PCSK9 was lowered by as much as 84 percent in the cohorts that received higher infusion rates of the treatment. At those higher treatment doses, Verve scientists said that the reduction of those LDL-C-related proteins lasted 2.5 years in previous studies on primates.

VERVE-101 explained visual.
Verve Therapeutics

From a clinical standpoint, this gene editing therapy has the potential to disrupt the current standard treatment for high cholesterol. The current go-to's include prescription statins and PCSK9 inhibitors, but they require strict adherence and can have bad side effects like muscle pain and memory loss.

CRISPR, while seemingly miraculous, is a long way from replacing daily medications though. According to Nature, two of the 10 participants in the study suffered from a “cardiovascular event” that coincided with the infusion. Verve says one was not related to the treatment at all and the second was “potentially related to treatment due to proximity to dosing.” The use of a gene-editing technology will always carry some risk because the edits could occur elsewhere in the genome.

Before a single infusion therapy for high cholesterol can reach consumers, the FDA mandates that the treatment will need to be studied for up to 15 years. Verve recently received FDA clearance for an Investigational New Drug Application for VERVE-101, meaning that the company can begin to conduct trials in the US. The current trials in New Zealand and the United Kingdom will look for willing clinical trial participants to expand the study.

This article originally appeared on Engadget at https://www.engadget.com/researchers-developed-a-gene-editing-technology-that-reduces-bad-cholesterol-170040293.html?src=rss

Amazon Prime now comes with discounted access to One Medical health services

Amazon Prime subscribers now have access to a deeply discounted One Medical membership for primary care services. The company announced today that Prime members can sign up for just $99 a year, or $9 per month. A One Medical membership typically costs $199 annually. In addition to the individual plan, Prime members who sign up for One Medical can add up to five other people for $6 each.

Amazon announced its acquisition of One Medical in 2022 and finalized the $3.9 billion deal in February, when it began offering a temporary discount for One Medical memberships at $144 per year. It's now slashed that even further. One Medical has doctor's offices in major cities across the US, all of which will be available to Prime members who sign up. It offers all the basic health services, from annual physicals and maintenance for chronic conditions to same-day sick visits. One Medical also offers round-the-clock virtual care, or telehealth visits, and drop-in lab services. The membership doesn’t cover the cost of visits though; patients will still have to bill through their insurance or pay out of pocket. 

Amazon has been pushing heavily into healthcare in recent years, with prescription services and even its own video- and text-based virtual clinic now among the perks of a Prime subscription. The company made its Amazon Clinic available to all states in the US over the summer, and began offering generic prescriptions for $5 a month with its RxPass at the beginning of the year. Amazon has also started offering drone deliveries for prescriptions in College Station, Texas.

This article originally appeared on Engadget at https://www.engadget.com/amazon-prime-now-comes-with-discounted-access-to-one-medical-health-services-161500277.html?src=rss

Innovative muscle oxygen monitor helps take your workouts to the next level

Most people probably think that training for competitive sports is just a matter of repeating a series of exercises with increasing intensity. That, however, is an extremely simplistic and quite dangerous strategy because our bodies are just machines. Knowing when to push harder and when to stop isn’t just a matter of feeling it and athletes have to rely on medical science and equipment to properly set their pace. That can be quite costly and inconvenient, especially for budding athletes or people with active lifestyles. Fortunately, you don’t need to break your wallet or become a scientist yourself just to get the information you need at the right time, thanks to this revolutionary wearable that lets you measure your muscle’s oxygen level so that you can train more efficiently and avoid injuries at the same time.

Designer: CLOMP

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

While heart rate monitors and blood oxygen (SpO2) monitors are important health indicators, they aren’t the only factors to consider when exercising, whether it’s for an upcoming competition or simply getting into shape. Oxygen saturation in muscles or SmO2 is just as critical because it’s what draws the line between just pushing the limits and fatigue. You can be breathing normally or taking in lots of oxygen, but your muscles might not actually be getting them properly. Unfortunately, this is something that can’t be accurately measured by smartwatches or trackers, and traditional methods are either too invasive or too bulky to really help athletes. That’s where CLOMP comes in, a muscle oxygen measurement device that you wear around your thigh to deliver real-time data without getting in your way.

CLOMP works by utilizing medical-grade functional near-infrared spectroscopy or fNIRS, the same technology used to monitor brain activity, oxygenation, and blood flow. It works almost in the same way as SpO2 or blood oxygen sensors that shine light through the skin and measure the reflected light to determine how much oxygen is being carried by the hemoglobin and myoglobin molecules in muscles and tissues. It’s an effective way to do non-invasive Lactate Threshold (LT) tests that tell when fatigue is about to set in.

With this information at hand, you or your coach can determine the most optimal training strategy while also reducing the risk of injury. It can even measure how much fat you’re burning by correlating muscle oxygen saturation (SmO2) with O2 intake and CO2 outtake, allowing you to tailor your training intensity based on your diet and calorie goals.

Despite its advanced functionality, using CLOMP couldn’t be easier. You simply strap the exercise band or patch on your thigh and you’re literally good to go. The wearable is so lightweight and ergonomic that it won’t drag you down and add to your body’s stress. CLOMP gathers data as you train and feeds it to the CLOMP app on your connected smartphone, where this data is interpreted and presented in a way that’s easy to digest and take action on.

Like many smart health platforms today, CLOMP will be able to use this information to not only guide you but also to suggest personalized workout plans, designed with USA Triathlon certified coach Gerardo Barrios, that fit your specific body’s needs and goals.

As with many things in life, the secret to training and exercise success isn’t just a matter of working harder. You also need to be smarter and more efficient, pushing your body to the limits while reducing the risk of injuries. That requires keeping track of the different biometrics of your body, which has traditionally been costly and cumbersome to do. With the CLOMP muscle oxygen measuring device, you get a medical-grade device to get the personalized information you need in a comfortable and ergonomic wearable that helps you work your way to gold the smarter and safer way.

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

The post Innovative muscle oxygen monitor helps take your workouts to the next level first appeared on Yanko Design.

Innovative muscle oxygen monitor helps take your workouts to the next level

Most people probably think that training for competitive sports is just a matter of repeating a series of exercises with increasing intensity. That, however, is an extremely simplistic and quite dangerous strategy because our bodies are just machines. Knowing when to push harder and when to stop isn’t just a matter of feeling it and athletes have to rely on medical science and equipment to properly set their pace. That can be quite costly and inconvenient, especially for budding athletes or people with active lifestyles. Fortunately, you don’t need to break your wallet or become a scientist yourself just to get the information you need at the right time, thanks to this revolutionary wearable that lets you measure your muscle’s oxygen level so that you can train more efficiently and avoid injuries at the same time.

Designer: CLOMP

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

While heart rate monitors and blood oxygen (SpO2) monitors are important health indicators, they aren’t the only factors to consider when exercising, whether it’s for an upcoming competition or simply getting into shape. Oxygen saturation in muscles or SmO2 is just as critical because it’s what draws the line between just pushing the limits and fatigue. You can be breathing normally or taking in lots of oxygen, but your muscles might not actually be getting them properly. Unfortunately, this is something that can’t be accurately measured by smartwatches or trackers, and traditional methods are either too invasive or too bulky to really help athletes. That’s where CLOMP comes in, a muscle oxygen measurement device that you wear around your thigh to deliver real-time data without getting in your way.

CLOMP works by utilizing medical-grade functional near-infrared spectroscopy or fNIRS, the same technology used to monitor brain activity, oxygenation, and blood flow. It works almost in the same way as SpO2 or blood oxygen sensors that shine light through the skin and measure the reflected light to determine how much oxygen is being carried by the hemoglobin and myoglobin molecules in muscles and tissues. It’s an effective way to do non-invasive Lactate Threshold (LT) tests that tell when fatigue is about to set in.

With this information at hand, you or your coach can determine the most optimal training strategy while also reducing the risk of injury. It can even measure how much fat you’re burning by correlating muscle oxygen saturation (SmO2) with O2 intake and CO2 outtake, allowing you to tailor your training intensity based on your diet and calorie goals.

Despite its advanced functionality, using CLOMP couldn’t be easier. You simply strap the exercise band or patch on your thigh and you’re literally good to go. The wearable is so lightweight and ergonomic that it won’t drag you down and add to your body’s stress. CLOMP gathers data as you train and feeds it to the CLOMP app on your connected smartphone, where this data is interpreted and presented in a way that’s easy to digest and take action on.

Like many smart health platforms today, CLOMP will be able to use this information to not only guide you but also to suggest personalized workout plans, designed with USA Triathlon certified coach Gerardo Barrios, that fit your specific body’s needs and goals.

As with many things in life, the secret to training and exercise success isn’t just a matter of working harder. You also need to be smarter and more efficient, pushing your body to the limits while reducing the risk of injuries. That requires keeping track of the different biometrics of your body, which has traditionally been costly and cumbersome to do. With the CLOMP muscle oxygen measuring device, you get a medical-grade device to get the personalized information you need in a comfortable and ergonomic wearable that helps you work your way to gold the smarter and safer way.

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

The post Innovative muscle oxygen monitor helps take your workouts to the next level first appeared on Yanko Design.

Innovative muscle oxygen monitor helps take your workouts to the next level

Most people probably think that training for competitive sports is just a matter of repeating a series of exercises with increasing intensity. That, however, is an extremely simplistic and quite dangerous strategy because our bodies are just machines. Knowing when to push harder and when to stop isn’t just a matter of feeling it and athletes have to rely on medical science and equipment to properly set their pace. That can be quite costly and inconvenient, especially for budding athletes or people with active lifestyles. Fortunately, you don’t need to break your wallet or become a scientist yourself just to get the information you need at the right time, thanks to this revolutionary wearable that lets you measure your muscle’s oxygen level so that you can train more efficiently and avoid injuries at the same time.

Designer: CLOMP

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

While heart rate monitors and blood oxygen (SpO2) monitors are important health indicators, they aren’t the only factors to consider when exercising, whether it’s for an upcoming competition or simply getting into shape. Oxygen saturation in muscles or SmO2 is just as critical because it’s what draws the line between just pushing the limits and fatigue. You can be breathing normally or taking in lots of oxygen, but your muscles might not actually be getting them properly. Unfortunately, this is something that can’t be accurately measured by smartwatches or trackers, and traditional methods are either too invasive or too bulky to really help athletes. That’s where CLOMP comes in, a muscle oxygen measurement device that you wear around your thigh to deliver real-time data without getting in your way.

CLOMP works by utilizing medical-grade functional near-infrared spectroscopy or fNIRS, the same technology used to monitor brain activity, oxygenation, and blood flow. It works almost in the same way as SpO2 or blood oxygen sensors that shine light through the skin and measure the reflected light to determine how much oxygen is being carried by the hemoglobin and myoglobin molecules in muscles and tissues. It’s an effective way to do non-invasive Lactate Threshold (LT) tests that tell when fatigue is about to set in.

With this information at hand, you or your coach can determine the most optimal training strategy while also reducing the risk of injury. It can even measure how much fat you’re burning by correlating muscle oxygen saturation (SmO2) with O2 intake and CO2 outtake, allowing you to tailor your training intensity based on your diet and calorie goals.

Despite its advanced functionality, using CLOMP couldn’t be easier. You simply strap the exercise band or patch on your thigh and you’re literally good to go. The wearable is so lightweight and ergonomic that it won’t drag you down and add to your body’s stress. CLOMP gathers data as you train and feeds it to the CLOMP app on your connected smartphone, where this data is interpreted and presented in a way that’s easy to digest and take action on.

Like many smart health platforms today, CLOMP will be able to use this information to not only guide you but also to suggest personalized workout plans, designed with USA Triathlon certified coach Gerardo Barrios, that fit your specific body’s needs and goals.

As with many things in life, the secret to training and exercise success isn’t just a matter of working harder. You also need to be smarter and more efficient, pushing your body to the limits while reducing the risk of injuries. That requires keeping track of the different biometrics of your body, which has traditionally been costly and cumbersome to do. With the CLOMP muscle oxygen measuring device, you get a medical-grade device to get the personalized information you need in a comfortable and ergonomic wearable that helps you work your way to gold the smarter and safer way.

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

The post Innovative muscle oxygen monitor helps take your workouts to the next level first appeared on Yanko Design.

Innovative muscle oxygen monitor helps take your workouts to the next level

Most people probably think that training for competitive sports is just a matter of repeating a series of exercises with increasing intensity. That, however, is an extremely simplistic and quite dangerous strategy because our bodies are just machines. Knowing when to push harder and when to stop isn’t just a matter of feeling it and athletes have to rely on medical science and equipment to properly set their pace. That can be quite costly and inconvenient, especially for budding athletes or people with active lifestyles. Fortunately, you don’t need to break your wallet or become a scientist yourself just to get the information you need at the right time, thanks to this revolutionary wearable that lets you measure your muscle’s oxygen level so that you can train more efficiently and avoid injuries at the same time.

Designer: CLOMP

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

While heart rate monitors and blood oxygen (SpO2) monitors are important health indicators, they aren’t the only factors to consider when exercising, whether it’s for an upcoming competition or simply getting into shape. Oxygen saturation in muscles or SmO2 is just as critical because it’s what draws the line between just pushing the limits and fatigue. You can be breathing normally or taking in lots of oxygen, but your muscles might not actually be getting them properly. Unfortunately, this is something that can’t be accurately measured by smartwatches or trackers, and traditional methods are either too invasive or too bulky to really help athletes. That’s where CLOMP comes in, a muscle oxygen measurement device that you wear around your thigh to deliver real-time data without getting in your way.

CLOMP works by utilizing medical-grade functional near-infrared spectroscopy or fNIRS, the same technology used to monitor brain activity, oxygenation, and blood flow. It works almost in the same way as SpO2 or blood oxygen sensors that shine light through the skin and measure the reflected light to determine how much oxygen is being carried by the hemoglobin and myoglobin molecules in muscles and tissues. It’s an effective way to do non-invasive Lactate Threshold (LT) tests that tell when fatigue is about to set in.

With this information at hand, you or your coach can determine the most optimal training strategy while also reducing the risk of injury. It can even measure how much fat you’re burning by correlating muscle oxygen saturation (SmO2) with O2 intake and CO2 outtake, allowing you to tailor your training intensity based on your diet and calorie goals.

Despite its advanced functionality, using CLOMP couldn’t be easier. You simply strap the exercise band or patch on your thigh and you’re literally good to go. The wearable is so lightweight and ergonomic that it won’t drag you down and add to your body’s stress. CLOMP gathers data as you train and feeds it to the CLOMP app on your connected smartphone, where this data is interpreted and presented in a way that’s easy to digest and take action on.

Like many smart health platforms today, CLOMP will be able to use this information to not only guide you but also to suggest personalized workout plans, designed with USA Triathlon certified coach Gerardo Barrios, that fit your specific body’s needs and goals.

As with many things in life, the secret to training and exercise success isn’t just a matter of working harder. You also need to be smarter and more efficient, pushing your body to the limits while reducing the risk of injuries. That requires keeping track of the different biometrics of your body, which has traditionally been costly and cumbersome to do. With the CLOMP muscle oxygen measuring device, you get a medical-grade device to get the personalized information you need in a comfortable and ergonomic wearable that helps you work your way to gold the smarter and safer way.

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

The post Innovative muscle oxygen monitor helps take your workouts to the next level first appeared on Yanko Design.

Innovative muscle oxygen monitor helps take your workouts to the next level

Most people probably think that training for competitive sports is just a matter of repeating a series of exercises with increasing intensity. That, however, is an extremely simplistic and quite dangerous strategy because our bodies are just machines. Knowing when to push harder and when to stop isn’t just a matter of feeling it and athletes have to rely on medical science and equipment to properly set their pace. That can be quite costly and inconvenient, especially for budding athletes or people with active lifestyles. Fortunately, you don’t need to break your wallet or become a scientist yourself just to get the information you need at the right time, thanks to this revolutionary wearable that lets you measure your muscle’s oxygen level so that you can train more efficiently and avoid injuries at the same time.

Designer: CLOMP

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

While heart rate monitors and blood oxygen (SpO2) monitors are important health indicators, they aren’t the only factors to consider when exercising, whether it’s for an upcoming competition or simply getting into shape. Oxygen saturation in muscles or SmO2 is just as critical because it’s what draws the line between just pushing the limits and fatigue. You can be breathing normally or taking in lots of oxygen, but your muscles might not actually be getting them properly. Unfortunately, this is something that can’t be accurately measured by smartwatches or trackers, and traditional methods are either too invasive or too bulky to really help athletes. That’s where CLOMP comes in, a muscle oxygen measurement device that you wear around your thigh to deliver real-time data without getting in your way.

CLOMP works by utilizing medical-grade functional near-infrared spectroscopy or fNIRS, the same technology used to monitor brain activity, oxygenation, and blood flow. It works almost in the same way as SpO2 or blood oxygen sensors that shine light through the skin and measure the reflected light to determine how much oxygen is being carried by the hemoglobin and myoglobin molecules in muscles and tissues. It’s an effective way to do non-invasive Lactate Threshold (LT) tests that tell when fatigue is about to set in.

With this information at hand, you or your coach can determine the most optimal training strategy while also reducing the risk of injury. It can even measure how much fat you’re burning by correlating muscle oxygen saturation (SmO2) with O2 intake and CO2 outtake, allowing you to tailor your training intensity based on your diet and calorie goals.

Despite its advanced functionality, using CLOMP couldn’t be easier. You simply strap the exercise band or patch on your thigh and you’re literally good to go. The wearable is so lightweight and ergonomic that it won’t drag you down and add to your body’s stress. CLOMP gathers data as you train and feeds it to the CLOMP app on your connected smartphone, where this data is interpreted and presented in a way that’s easy to digest and take action on.

Like many smart health platforms today, CLOMP will be able to use this information to not only guide you but also to suggest personalized workout plans, designed with USA Triathlon certified coach Gerardo Barrios, that fit your specific body’s needs and goals.

As with many things in life, the secret to training and exercise success isn’t just a matter of working harder. You also need to be smarter and more efficient, pushing your body to the limits while reducing the risk of injuries. That requires keeping track of the different biometrics of your body, which has traditionally been costly and cumbersome to do. With the CLOMP muscle oxygen measuring device, you get a medical-grade device to get the personalized information you need in a comfortable and ergonomic wearable that helps you work your way to gold the smarter and safer way.

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

The post Innovative muscle oxygen monitor helps take your workouts to the next level first appeared on Yanko Design.

Innovative muscle oxygen monitor helps take your workouts to the next level

Most people probably think that training for competitive sports is just a matter of repeating a series of exercises with increasing intensity. That, however, is an extremely simplistic and quite dangerous strategy because our bodies are just machines. Knowing when to push harder and when to stop isn’t just a matter of feeling it and athletes have to rely on medical science and equipment to properly set their pace. That can be quite costly and inconvenient, especially for budding athletes or people with active lifestyles. Fortunately, you don’t need to break your wallet or become a scientist yourself just to get the information you need at the right time, thanks to this revolutionary wearable that lets you measure your muscle’s oxygen level so that you can train more efficiently and avoid injuries at the same time.

Designer: CLOMP

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

While heart rate monitors and blood oxygen (SpO2) monitors are important health indicators, they aren’t the only factors to consider when exercising, whether it’s for an upcoming competition or simply getting into shape. Oxygen saturation in muscles or SmO2 is just as critical because it’s what draws the line between just pushing the limits and fatigue. You can be breathing normally or taking in lots of oxygen, but your muscles might not actually be getting them properly. Unfortunately, this is something that can’t be accurately measured by smartwatches or trackers, and traditional methods are either too invasive or too bulky to really help athletes. That’s where CLOMP comes in, a muscle oxygen measurement device that you wear around your thigh to deliver real-time data without getting in your way.

CLOMP works by utilizing medical-grade functional near-infrared spectroscopy or fNIRS, the same technology used to monitor brain activity, oxygenation, and blood flow. It works almost in the same way as SpO2 or blood oxygen sensors that shine light through the skin and measure the reflected light to determine how much oxygen is being carried by the hemoglobin and myoglobin molecules in muscles and tissues. It’s an effective way to do non-invasive Lactate Threshold (LT) tests that tell when fatigue is about to set in.

With this information at hand, you or your coach can determine the most optimal training strategy while also reducing the risk of injury. It can even measure how much fat you’re burning by correlating muscle oxygen saturation (SmO2) with O2 intake and CO2 outtake, allowing you to tailor your training intensity based on your diet and calorie goals.

Despite its advanced functionality, using CLOMP couldn’t be easier. You simply strap the exercise band or patch on your thigh and you’re literally good to go. The wearable is so lightweight and ergonomic that it won’t drag you down and add to your body’s stress. CLOMP gathers data as you train and feeds it to the CLOMP app on your connected smartphone, where this data is interpreted and presented in a way that’s easy to digest and take action on.

Like many smart health platforms today, CLOMP will be able to use this information to not only guide you but also to suggest personalized workout plans, designed with USA Triathlon certified coach Gerardo Barrios, that fit your specific body’s needs and goals.

As with many things in life, the secret to training and exercise success isn’t just a matter of working harder. You also need to be smarter and more efficient, pushing your body to the limits while reducing the risk of injuries. That requires keeping track of the different biometrics of your body, which has traditionally been costly and cumbersome to do. With the CLOMP muscle oxygen measuring device, you get a medical-grade device to get the personalized information you need in a comfortable and ergonomic wearable that helps you work your way to gold the smarter and safer way.

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

The post Innovative muscle oxygen monitor helps take your workouts to the next level first appeared on Yanko Design.

Innovative muscle oxygen monitor helps take your workouts to the next level

Most people probably think that training for competitive sports is just a matter of repeating a series of exercises with increasing intensity. That, however, is an extremely simplistic and quite dangerous strategy because our bodies are just machines. Knowing when to push harder and when to stop isn’t just a matter of feeling it and athletes have to rely on medical science and equipment to properly set their pace. That can be quite costly and inconvenient, especially for budding athletes or people with active lifestyles. Fortunately, you don’t need to break your wallet or become a scientist yourself just to get the information you need at the right time, thanks to this revolutionary wearable that lets you measure your muscle’s oxygen level so that you can train more efficiently and avoid injuries at the same time.

Designer: CLOMP

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

While heart rate monitors and blood oxygen (SpO2) monitors are important health indicators, they aren’t the only factors to consider when exercising, whether it’s for an upcoming competition or simply getting into shape. Oxygen saturation in muscles or SmO2 is just as critical because it’s what draws the line between just pushing the limits and fatigue. You can be breathing normally or taking in lots of oxygen, but your muscles might not actually be getting them properly. Unfortunately, this is something that can’t be accurately measured by smartwatches or trackers, and traditional methods are either too invasive or too bulky to really help athletes. That’s where CLOMP comes in, a muscle oxygen measurement device that you wear around your thigh to deliver real-time data without getting in your way.

CLOMP works by utilizing medical-grade functional near-infrared spectroscopy or fNIRS, the same technology used to monitor brain activity, oxygenation, and blood flow. It works almost in the same way as SpO2 or blood oxygen sensors that shine light through the skin and measure the reflected light to determine how much oxygen is being carried by the hemoglobin and myoglobin molecules in muscles and tissues. It’s an effective way to do non-invasive Lactate Threshold (LT) tests that tell when fatigue is about to set in.

With this information at hand, you or your coach can determine the most optimal training strategy while also reducing the risk of injury. It can even measure how much fat you’re burning by correlating muscle oxygen saturation (SmO2) with O2 intake and CO2 outtake, allowing you to tailor your training intensity based on your diet and calorie goals.

Despite its advanced functionality, using CLOMP couldn’t be easier. You simply strap the exercise band or patch on your thigh and you’re literally good to go. The wearable is so lightweight and ergonomic that it won’t drag you down and add to your body’s stress. CLOMP gathers data as you train and feeds it to the CLOMP app on your connected smartphone, where this data is interpreted and presented in a way that’s easy to digest and take action on.

Like many smart health platforms today, CLOMP will be able to use this information to not only guide you but also to suggest personalized workout plans, designed with USA Triathlon certified coach Gerardo Barrios, that fit your specific body’s needs and goals.

As with many things in life, the secret to training and exercise success isn’t just a matter of working harder. You also need to be smarter and more efficient, pushing your body to the limits while reducing the risk of injuries. That requires keeping track of the different biometrics of your body, which has traditionally been costly and cumbersome to do. With the CLOMP muscle oxygen measuring device, you get a medical-grade device to get the personalized information you need in a comfortable and ergonomic wearable that helps you work your way to gold the smarter and safer way.

Click Here to Buy Now: $259 $420 ($161 off). Hurry, only 3 left!

The post Innovative muscle oxygen monitor helps take your workouts to the next level first appeared on Yanko Design.