Blind woman may see thanks to gene therapy and light

Optogenetics, or mixing gene therapy with light treatments, is finally getting a proper field test: doctors have given a blind Texas woman the first optogenetics-based therapy in hopes of restoring some of the vision lost to a degenerative retina dis...

Microchip implant lets blind patients see shapes, skip the prosthetic

Microchip implant lets blind patients see light, skip the glasses

An eye-implanted chip from Retina Implant has restored patients' ability to discern light during its latest trial, according to German researchers. The device works in a similar fashion to the newly FDA-approved Argus II retinal prosthesis to return limited vision in patients with photoreceptor cell diseases like retinitis pigmentosa. Unlike that system, however, light is picked up via 1,500 pixels on a retinal implant instead of an eyeglass-mounted camera. The signal is boosted by a coil implanted in skin behind the ear and sent back to so-called bipolar cells still active on the retina, which in turn send an image to the brain through regular neural circuits. A small battery mounted behind the ear -- the only external sign of the device -- contains controls for brightness and contrast. The recent trial let 8 out of 9 patients see in varying degrees, with three in the study even able to read letters and see the faces of family members. Given that the Argus II finally crossed the FDA's bionic eye barrier, hopefully we won't have to wait nearly as long for research like this to become a product.

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Via: MIT Technology Review

Source: Royal B Society

FDA clears Argus II ‘bionic eye’ for sale in the US (video)

FDA clears Argus II 'bionic eye' for sale in the US video

Those in the US suffering from blindness due to retinis pigmentosa (RP) will now be able to regain some vision bionically for the first time ever, thanks to Second Sight's Argus II retinal prosthesis. The device was just approved by the FDA for sale stateside after surmounting the same hurdle in Europe almost two years ago -- though it was first launched long, long before that. RP is a rare genetic disease that inflicts 100,000 or so Americans, destroying photoreceptors in the eye while leaving other cells intact. By implanting a device on the retina that receives a signal from the eyeglass-mounted camera, those cells can be stimulated as if receiving light, causing them to transmit an image to the brain. Due to the limited number of electrodes, patients would only be able to discern light or dark, but most have reported better functionality with the device -- being able to make out the shape of a curb while walking, or discerning between light, grey or dark colored socks, for instance. The Argus II has been certified by the FDA for "humanitarian use," meaning there's "reasonable assurance" that it's safe, and should start popping up in specialized clinics by the end of the year.

[Photo credit: Associated Press]

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Via: CNET