Neuralink successfully implants its chip into a second patient’s brain

Neuralink's brain chip has been implanted into a second patient as part of early human trials, Elon Musk told podcast host Lex Fridman on Saturday. The company hasn't disclosed when the surgery took place or the name of the recipient, according to Reuters.

Musk said 400 of the electrodes on the second patient's brain are working out of 1,024 implanted. "I don't want to jinx it but it seems to have gone extremely well," he said. "There's a lot of signal, a lot of electrodes. It's working very well." 

The device allows patients with spinal cord injuries to play video games, use the internet and control electronic devices using their thoughts alone. In May, the company announced that it was "accepting applications for the second participant" in trials following FDA approval. 

The original Neuralink implant patient, Nolan Arbaugh, described the surgery as "super easy." In a demo, the company showed how Arbaugh was able to move a cursor around the screen of a laptop, pause an on-screen music device and play chess and Civilization VI.

Arbaugh himself participated in the marathon podcast with Musk and Fridman. He said that the device allows him to make anything happen on a computer screen just by thinking it, helping reduce his reliance on caregivers. 

However, problems cropped up shortly after his surgery when some of electrodes retracted from his brain. The issue was partly rectified later on by modifying the algorithm to make the implants more sensitive. Neuralink told the FDA that in a second procedure, it would place the implant’s threads deeper into the patient’s brain to prevent them from moving as much as they did in Arbaugh’s case.

Neuralink previously tested its implant in animals, including chimps, and some of those testing practices have been the subject of federal investigations

Despite those issues, the company said it had over 1,000 volunteers for its second surgical trial. Musk said he expects Neuralink to implant its chips in up to eight more patients by the end of 2024.  

This article originally appeared on Engadget at https://www.engadget.com/neuralink-successfully-implants-its-chip-into-a-second-patients-brain-123013864.html?src=rss

Breakthrough Titanium Heart Design Successfully Implanted in a Human

In a significant medical breakthrough, the Texas Heart Institute and BiVACOR have successfully implanted the BiVACOR Total Artificial Heart (TAH) in a human patient at Baylor St. Luke’s Medical Center. This development marks a substantial advancement in treating severe heart conditions, particularly for patients with biventricular and univentricular heart failure, who are unsuitable candidates for traditional devices like left ventricular assist devices.

Designer: BiVACOR

The BiVACOR TAH features a titanium rotary blood pump utilizing magnetic levitation technology. This innovation minimizes the wear and tear commonly seen in traditional artificial hearts. With only one moving part, the TAH emulates the human heart’s function by efficiently pumping blood while reducing damage to blood cells.

The maglev technology allows the rotor inside the heart to operate without contacting other parts, reducing friction and extending the device’s lifespan. Inspired by high-speed trains, this technology enables the artificial heart to function quietly and smoothly, enhancing patient comfort. The TAH is designed to sustain patients until a suitable donor heart is available for transplant.

This successful implantation is part of a U.S. Food and Drug Administration study to assess the TAH’s safety and effectiveness in real-world conditions. Daniel Timms, founder and CTO of BiVACOR, noted that this technology brings us closer to providing more options for patients ineligible for traditional heart transplants.

Heart failure is a leading cause of death worldwide, affecting millions. In the U.S. alone, about 6.2 million adults suffer from heart failure. The National Institutes of Health estimate that up to 100,000 U.S. patients could immediately benefit from mechanical heart support like the TAH.

Dr. Joseph Rogers, president and CEO of the Texas Heart Institute, emphasized the importance of this new technology. Collaborating with BiVACOR and Baylor College of Medicine, they aim to revolutionize heart failure treatment and offer new hope to patients in need.

Comparing the Titanium Maglev Heart and the Biological Heart

The titanium maglev heart looks and functions quite differently from a natural human heart. Constructed from titanium, this heart implant features a strong, metallic design, which stands in stark contrast to the soft muscle tissue of a biological heart. The maglev heart’s sleek design includes various ports and connectors that allow it to work seamlessly with medical devices. Meanwhile, a biological heart has a more organic look, with textures and colors that highlight its living nature, without the industrial elements present in the titanium heart.

BiVACOR: The Total Artificial Heart, made of titanium

Design-wise, the maglev heart appears more mechanical, with visible joints and parts tailored for specific functions, resembling a machine more than an organ. Conversely, the biological heart is smooth and compact, with chambers and valves seamlessly flowing together without sharp edges or mechanical parts.

Functionally, the maglev heart includes technology for monitoring and control, allowing for potential remote adjustments. Its ports and cables are designed to connect to external devices. In contrast, the natural heart’s connections are biological, including arteries and veins, without external interfaces.

Size-wise, the titanium maglev heart may be larger than a biological heart due to the space required for mechanical components like motors and the magnetic levitation system. A biological heart is typically more compact, fitting efficiently within the chest cavity.

The titanium maglev heart shows how science and engineering can merge to provide new solutions for patients who cannot receive a biological heart transplant. Its design and features highlight advancements in medical devices, offering a promising option for those in need.

The post Breakthrough Titanium Heart Design Successfully Implanted in a Human first appeared on Yanko Design.

Meta gives researchers access to Instagram data for teen mental health study

Serious concerns have been raised about the effect of social media on teenagers’ mental well-being. Meta is letting a group of researchers examine some of Instagram’s data to determine if social media is psychologically damaging younger users.

The Verge reported that the Center for Open Science (COS) is launching a new joint pilot program with Meta to produce independent studies about how social media affects teenagers’ mental health.

The Instagram Data Access Pilot for Well-Being Research program will conduct “independent academic” research using up to six months of Instagram data to determine the “potential positive or negative associations of Instagram use” among teens and young adults. The study will also examine the positive and negative differences of large populations across the world and the causes of “statistical relationships between Instagram and social or emotional health,” according to the program’s website.

The data researchers can access may include an Instagram user’s followers and the accounts they follow, account settings and the amount of time they spend on the photo sharing service. The researchers will not have access to users’ demographic information or the contents of their posts and comments. The data will come from accounts based in 24 countries including the US and UK, according to the request for proposal (RFP).

Other scientific studies conducted by researchers from the Massachusetts Institute of Technology (MIT) and New York University and Stanford have found parallel links between social media use and the state of a person’s mental health. The link earned greater awareness last year when Arturo Béjar, a former director of engineering for Protect and Care at Facebook, testified before a Senate Judiciary subcommittee that he alerted the company and its CEO Mark Zuckerberg by email of the dangers their product could have on young people.

Béjar testified that seven days before the hearing, 13 percent of users on Instagram between the ages of 13-15 receive unwanted sexual advances. He also testified that his own 16-year-old daughter exhibited signs of a momentary decline in mental health when a user commented that she should “get back to the kitchen” under one of her posts.

A month before the hearing, 41 states filed a lawsuit against Meta for allegedly misleading the public about the potentially addictive nature of its platforms like Facebook and Instagram among teenagers.

"My experience, after sending that email and seeing what happened afterwards, is that they knew there were things they could do about it, they chose not to do them and we cannot trust them with our children," Béjar said during the hearing. "It's time for Congress to act. The evidence, I believe, is overwhelming."

This article originally appeared on Engadget at https://www.engadget.com/meta-gives-researchers-access-to-instagram-data-for-teen-mental-health-study-204322979.html?src=rss

Epileptic teen receives first ever seizure-controlling brain implant

A 13-year-old boy with severe epilepsy in the United Kingdom has become the first person in the world to receive a brain implant that helps keep seizures under control. Per The Guardian, Oran Knowlson underwent surgery at Great Ormond Street Hospital (GOSH) in London to have the Picostim neurostimulator fitted into his brain to address Lennox-Gastaut syndrome, a rare treatment-resistant form of epilepsy.

Knowlson received the neurostimulator in October 2023 as part of a pilot program run by GOSH in collaboration with University College London, King’s College Hospital and the University of Oxford. Since receiving the implant, which was developed by Amber Therapeutics, Oran’s daytime seizures have been reduced by 80 percent. Previously, his seizures were so severe he required constant care, and would sometimes lose consciousness and need resuscitation.

“For Oran and his family, epilepsy completely changed their lives and so to see him riding a horse and getting his independence back is absolutely astounding,” said Martin Tisdall, the pediatric neurosurgeon at GOSH. “We couldn’t be happier to be part of their journey.”

Tisdall’s surgical team installed the implant by mounting the Picostim to Knowlson's skull and inserting two electrodes deep into his brain until they hit the thalamus. The electrodes were then connected to the neurostimulator, which sends constant, mild electrical current to his brain to prevent or attenuate seizures. Justine Knowlson, Oran’s mother, confirmed as much when she discussed how the implant improved her son’s quality of life.

“We’ve seen a big improvement; seizures have reduced and are less severe,” she said. “He’s a lot more chatty, he’s more engaged. He’s turned 13 and I definitely now have a teenager – he’s happy to tell me no. But that adds to his quality of life, when he can express himself better.”

The Picostim neurostimulator is just one device for seizure treatment being tested. In 2020, researchers in Israel developed a wearable EEG device called Epiness, which can predict seizures up to an hour before they start. Two years earlier, a smart arm bracelet called Nightwatch was created to detect nighttime epileptic seizures and contact the wearer’s care staff when they strike.

This article originally appeared on Engadget at https://www.engadget.com/epileptic-teen-receives-first-ever-seizure-controlling-brain-implant-193617887.html?src=rss

The world’s first tooth-regrowing drug has been approved for human trials

I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials.

The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. The intravenous drug deactivates the uterine sensitization-associated gene-1 (USAG-1) protein that suppresses tooth growth. Blocking USAG-1 from interacting with other proteins triggers bone growth and, voila, you got yourself some brand-new chompers. Pretty cool, right?

Human trials start in September, but the drug has been highly successful when treating ferrets and mice and did its job with no serious side effects. Of course, the usual caveat applies. Humans are not mice or ferrets, though researchers seem confident that it’ll work on homo sapiens. This is due to a 97 percent similarity in how the USAG-1 protein works when comparing humans to other species.

September’s clinical trial will include adults who are missing at least one molar but there’s a secondary trial coming aimed at children aged two to seven. The kids in the second trial will all be missing at least four teeth due to congenital tooth deficiency. Finally, a third trial will focus on older adults who are missing “one to five permanent teeth due to environmental factors.”

Takahashi and his fellow researchers are so optimistic about this drug that they predict the medicine will be available for everyday consumers by 2030. So in six years we can throw our toothbrushes away and eat candy bars all day and all night without a care in the world (don’t actually do that.)

While this is the first drug that can fully regrow missing teeth, the science behind it builds on top of years of related research. Takahashi, after all, has been working on this since 2005. Recent advancements in the field include regenerative tooth fillings to repair diseased teeth and stem cell technology to regrow the dental tissue of children.

This article originally appeared on Engadget at https://www.engadget.com/the-worlds-first-tooth-regrowing-drug-has-been-approved-for-human-trials-174423381.html?src=rss

The world’s first tooth-regrowing drug has been approved for human trials

I remember being a kid and seeing my grandmother without her dentures for the first time. It was a harrowing experience. Now my dad has dentures so, genetically speaking, I’m several decades out from needing some myself. However, it’s possible that modern medicine will solve the issue of lost teeth by then, thanks to a new drug that's about to enter human trials.

The medicine quite literally regrows teeth and was developed by a team of Japanese researchers, as reported by New Atlas. The research has been led by Katsu Takahashi, head of dentistry and oral surgery at Kitano Hospital. The intravenous drug deactivates the uterine sensitization-associated gene-1 (USAG-1) protein that suppresses tooth growth. Blocking USAG-1 from interacting with other proteins triggers bone growth and, voila, you got yourself some brand-new chompers. Pretty cool, right?

Human trials start in September, but the drug has been highly successful when treating ferrets and mice and did its job with no serious side effects. Of course, the usual caveat applies. Humans are not mice or ferrets, though researchers seem confident that it’ll work on homo sapiens. This is due to a 97 percent similarity in how the USAG-1 protein works when comparing humans to other species.

September’s clinical trial will include adults who are missing at least one molar but there’s a secondary trial coming aimed at children aged two to seven. The kids in the second trial will all be missing at least four teeth due to congenital tooth deficiency. Finally, a third trial will focus on older adults who are missing “one to five permanent teeth due to environmental factors.”

Takahashi and his fellow researchers are so optimistic about this drug that they predict the medicine will be available for everyday consumers by 2030. So in six years we can throw our toothbrushes away and eat candy bars all day and all night without a care in the world (don’t actually do that.)

While this is the first drug that can fully regrow missing teeth, the science behind it builds on top of years of related research. Takahashi, after all, has been working on this since 2005. Recent advancements in the field include regenerative tooth fillings to repair diseased teeth and stem cell technology to regrow the dental tissue of children.

This article originally appeared on Engadget at https://www.engadget.com/the-worlds-first-tooth-regrowing-drug-has-been-approved-for-human-trials-174423381.html?src=rss

Diet-friendly electric spoon enhances saltiness in food without actual salt

It’s almost too easy to take salt for granted these days given how common it is, but there was a time long ago when it was as valuable as gold. The role that salt and salty flavors play in our lives becomes all too apparent the moment we taste bland food, resulting in requesting for seasoning or, well, salt. Too much salt, however, put people’s health at risk, especially in cultures that lean towards very salty dishes. Replacing salt with healthier alternatives might just be a stopgap solution, so this innovative electric spoon simply tries to trick our tongues into tasting saltiness where there is barely any salt, allowing people to consume less salt without actual giving up their favorite flavor.

Designer: Kirin

Simple as it may look, our tongues are really complex systems of taste buds that may react different depending on their location and sensitivity to certain flavors. We’ve all been through science experiments related to the different areas of the tongue as well as how weak electrical currents, like those from a lemon, can affect our sense of taste. The latter is the principle behind this simple-looking electric salt spoon that aims to promote a healthier diet by reducing the amount of salt you need to use or consume just to get that salty flavor you love.

In a nutshell, the plastic and metal spoon passes a very weak electrical current on your tongue that tries to draw sodium ions that are normally dispersed and wasted, enhancing the salty flavor that would have otherwise been lost normally. This does mean that the salty flavor doesn’t just magically appear and there needs to still be some amount of salt in the dish for the magic to work. That said, the technology promises 1.5 times more saltiness, which mean you can use 1.5 times less salt to taste the same flavor. For a food culture like Japan that consumes 10g of salt daily, much higher than what the World Health Organization (WHO) recommends, that’s still a significant reduction.

The design of the spoon itself is pretty basic, and its large handle almost makes it look and feel like a child’s spoon. Operating the electric spoon is a simple matter of pressing a single button to turn it on and cycling through different electrical intensities. Amusingly, they recommend a proper way of holding the spoon and positioning your arm in order to maximize the effect of the weak current provided by a rechargeable lithium battery.

It might be a weird idea to be giving your tongue a tiny electrical shock to make food taste saltier, and the company behind the innovation promises it’s all within safe ranges. While it’s not going to make food magically taste better, the electric salt spoon offers a simpler, and somewhat more affordable way to enjoy low-salt diets without resorting to expensive salt alternatives.

The post Diet-friendly electric spoon enhances saltiness in food without actual salt first appeared on Yanko Design.

Another patient will get Neuralink’s brain implant

Neuralink will be able to surgically implant its device into another patient’s brain. The Wall Street Journal reports that the company was approved to move forward with a second procedure months after Noland Arbaugh became the first person to receive the brain implant.

Elon Musk said last week that the company was “accepting applications for the second participant” in the trial. The company began recruiting potential participants for its first clinical trial last year with the goal of bringing the technology to people with ALS, spinal cord injuries or other conditions that cause quadriplegia.

Neuralink has also reportedly come up with a potential fix for an issue that caused Arbaugh’s implant to malfunction about a month after his surgery. The company said earlier this month that some of the implant’s threads “retracted from the brain” causing the issue. Arbaugh recently told Bloomberg that software updates have since restored many of those capabilities. Neuralink has shared clips of Arbaugh, who is paralyzed from the neck down, playing chess, controlling a music player app and performing other activities. 

According to The Journal, Neuralink told the FDA that in a second procedure it would place the implant’s threads deeper into the patient’s brain to prevent them from moving as much as they did in Arbaugh’s case. The FDA is apparently on board with the changes. The company reportedly wants to complete the second surgery in June and has seen more than 1,000 people sign up for a chance to participate in the trial.

This article originally appeared on Engadget at https://www.engadget.com/another-patient-will-get-neuralinks-brain-implant-235059248.html?src=rss

EU investigating Meta over addiction and safety concerns for minors

Meta is back in hot water for its methods (or lack thereof) for protecting children. The European Commission has launched formal proceedings to determine whether the owner of Facebook and Instagram has violated the Digital Services Act (DSA) by contributing to children's social media addiction and not ensuring they have high levels of safety and privacy.

The Commission's investigation will specifically examine whether Meta is properly assessing and acting against risks brought on by its platforms' interfaces. It's concerned about how their designs could "exploit the weaknesses and inexperience of minors and cause addictive behavior, and/or reinforce so-called 'rabbit hole' effect. Such an assessment is required to counter potential risks for the exercise of the fundamental right to the physical and mental well-being of children as well as to the respect of their rights."

The proceedings will also explore whether Meta takes necessary steps to prevent minors from accessing inappropriate content, has effective age-verification tools and minors have straightforward, strong privacy tools, such as default settings.

The DSA sets standards for very large online platforms and search engines (those with 45 million or more monthly users in the EU) like Meta. Obligations for designated companies include transparency about advertising and content moderation decisions, sharing their data with the Commission and looking into risks their systems pose related to areas such as gender-based violence, mental health and protection of minors.

Meta responded to the formal proceedings by pointing to features such as parental supervision settings, quiet mode and it automatically restricting content for teens. "We want young people to have safe, age-appropriate experiences online and have spent a decade developing more than 50 tools and policies designed to protect them. This is a challenge the whole industry is facing, and we look forward to sharing details of our work with the European Commission," a Meta spokesperson told Engadget.

However, Meta has continuously failed to prioritize the safety of young people. Previous alarming incidents include Instagram's algorithm suggesting content that features child sexual exploitation and claims that it designs its platforms to be addictive to young people while suggesting psychologically harmful content, such as the promotion of eating disorders and body dysmorphia.

Meta has also famously served as a hub of misinformation for people of all ages. The Commission already launched formal proceedings against the company on April 30 due to concerns around deceptive advertising, data access for researchers and the lack of an "effective third-party real-time civic discourse and election-monitoring tool" before June's European Parliament elections, among other concerns. Earlier this year, Meta announced that CrowdTangle, which has publicly shown how fake news and conspiracy theories move around Facebook and Instagram, would be completely shut down in August.

This article originally appeared on Engadget at https://www.engadget.com/eu-investigating-meta-over-addiction-and-safety-concerns-for-minors-120709921.html?src=rss

EU investigating Meta over addiction and safety concerns for minors

Meta is back in hot water for its methods (or lack thereof) for protecting children. The European Commission has launched formal proceedings to determine whether the owner of Facebook and Instagram has violated the Digital Services Act (DSA) by contributing to children's social media addiction and not ensuring they have high levels of safety and privacy.

The Commission's investigation will specifically examine whether Meta is properly assessing and acting against risks brought on by its platforms' interfaces. It's concerned about how their designs could "exploit the weaknesses and inexperience of minors and cause addictive behavior, and/or reinforce so-called 'rabbit hole' effect. Such an assessment is required to counter potential risks for the exercise of the fundamental right to the physical and mental well-being of children as well as to the respect of their rights."

The proceedings will also explore whether Meta takes necessary steps to prevent minors from accessing inappropriate content, has effective age-verification tools and minors have straightforward, strong privacy tools, such as default settings.

The DSA sets standards for very large online platforms and search engines (those with 45 million or more monthly users in the EU) like Meta. Obligations for designated companies include transparency about advertising and content moderation decisions, sharing their data with the Commission and looking into risks their systems pose related to areas such as gender-based violence, mental health and protection of minors.

Meta responded to the formal proceedings by pointing to features such as parental supervision settings, quiet mode and it automatically restricting content for teens. "We want young people to have safe, age-appropriate experiences online and have spent a decade developing more than 50 tools and policies designed to protect them. This is a challenge the whole industry is facing, and we look forward to sharing details of our work with the European Commission," a Meta spokesperson told Engadget.

However, Meta has continuously failed to prioritize the safety of young people. Previous alarming incidents include Instagram's algorithm suggesting content that features child sexual exploitation and claims that it designs its platforms to be addictive to young people while suggesting psychologically harmful content, such as the promotion of eating disorders and body dysmorphia.

Meta has also famously served as a hub of misinformation for people of all ages. The Commission already launched formal proceedings against the company on April 30 due to concerns around deceptive advertising, data access for researchers and the lack of an "effective third-party real-time civic discourse and election-monitoring tool" before June's European Parliament elections, among other concerns. Earlier this year, Meta announced that CrowdTangle, which has publicly shown how fake news and conspiracy theories move around Facebook and Instagram, would be completely shut down in August.

This article originally appeared on Engadget at https://www.engadget.com/eu-investigating-meta-over-addiction-and-safety-concerns-for-minors-120709921.html?src=rss